Patterns of electrical activity generated by biological neural network in vitro

Abstract

Cultured dissociated neurons forming network in vitro is a unique system representing living biological neural net- work developing in fully artificial conditions. This is a promising model for study of basic mechanisms of the brain functioning that requires special tools for interfacing and investigations. We have developed a set of devices and techniques for culturing of neural network on the surface of microelectrode sensor and registered specific patterns of electrical activity of the living neural network in vitro.