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Please use this identifier to cite or link to this item: https://libeldoc.bsuir.by/handle/123456789/54173
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dc.contributor.authorDrinevskyi, A.-
dc.contributor.authorZelkovskyi, E.-
dc.contributor.authorAbashkin, V.-
dc.contributor.authorShcharbin, D.-
dc.contributor.authorRysalskaya, T.-
dc.contributor.authorRadziuk, D. V.-
dc.coverage.spatialUSAen_US
dc.date.accessioned2024-01-31T07:18:14Z-
dc.date.available2024-01-31T07:18:14Z-
dc.date.issued2023-
dc.identifier.citationActivation of ibuprofen via ultrasonic complexation with silver in N-doped oxidized graphene nanoparticles for microwave chemotherapy of cervix tumor tissue / A. Drinevskyi [et al.] // ACS Biomaterials Science & Engineering. – 2023. – № 9(1). – P. 182–196.en_US
dc.identifier.urihttps://libeldoc.bsuir.by/handle/123456789/54173-
dc.description.abstractAn ultrasonic method (20 kHz) is introduced to activate pristine ibuprofen organic molecular crystals via complexation with silver in nitrogen-doped oxidized graphene nanoplatforms (∼50 nm). Ultra9 sonic complexation occurs in a single-step procedure through the binding of the carboxylic groups with Ag, H-bond formation, involving noncovalent πC=C → πC=C* transitions in the altered phenyl ring and πPY → πCO* in ibuprofen occurring between the phenyl ring and C−O bonds as a result of interaction with hydroxyl radicals. The ibuprofen−silver complex in ≪NrGO≫ exhibits a ∼42 times higher acceleration rate than free ibuprofen of the charge transfer between hexacyanoferrate and thiosulfate ions. The increased acceleration rate can be caused by electron injection/ejection at the interface of the ≪Ag-NrGO≫ nanoplatform and formation of intermediate species (Fe(CN)5(CNSO3)x− with x = 4 or 5 and AgHS2O3) at the excess of produced H+ ions. Important for microwave chemotherapy, ibuprofen−silver complexes in the ≪NrGO≫ nanoplatform can produce H+ ions at ∼12.5 times higher rate at the applied voltage range from 0.53 to 0.60 V. ≪Ibu-Ag-NrGO≫ NPs develop ∼105 order higher changes of the electric field strength intensity than free ibuprofen in the microwave absorption range of 100−1000 MHz as revealed from the theoretical modeling of a cervix tumor tissue.en_US
dc.language.isoenen_US
dc.publisherAmerican Chemical Societyen_US
dc.subjectпубликации ученыхen_US
dc.subjectcatalysisen_US
dc.subjectNSAIDen_US
dc.subjectgrapheneen_US
dc.subjectmicrowave chemotherapyen_US
dc.subjectcervixen_US
dc.titleActivation of ibuprofen via ultrasonic complexation with silver in N-doped oxidized graphene nanoparticles for microwave chemotherapy of cervix tumor tissueen_US
dc.typeArticleen_US
dc.identifier.DOIhttps://doi.org/10.1021/acsbiomaterials.2c01045-
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